MOTS-c
Mitochondrial-Derived Peptide
A 16-amino-acid mitochondrial-derived peptide encoded by the 12S rRNA gene. Studied for regulation of cellular energy metabolism through AMPK activation, improvement of insulin sensitivity, and mitochondrial biogenesis support.
Format
5mg / vial
Purity
>98.9%
Category
Longevity
Storage
2–8 °C
Research Price
€119
5mg / vial
RESEARCH USE ONLY
This compound is sold exclusively for in-vitro laboratory research. It is not intended for human consumption, therapeutic use, or self-administration. You must be 18+ and a qualified researcher to purchase.
Complete Your Research with the Pen Kit
Precise, painless, repeatable. The clinical-grade injection pen with 32G ultra-fine needles, bacteriostatic water, and your choice of peptide — ready to use out of the box.
€189
View details →Research Protocol Bundles
Longevity Protocol
Epithalon + MOTS-C + NAD+
Three compounds at the frontier of cellular longevity research — Epithalon for telomere maintenance, MOTS-C for mitochondrial signalling, and NAD+ precursor for metabolic cofactor support.
Bundle total
€277
12% bundle saving
Documented Research Parameters
Research Dose
5–10 mg
Frequency
3–5× per week
Duration
4–8 weeks
Half-Life
Not fully established; estimated 2–4 hours
Route(s)
Subcutaneous · Intramuscular
Solubility
Water
Reconstitution
2 ml bacteriostatic water per 5 mg vial
Key Research Findings
Encoded in the 12S rRNA locus of mitochondrial DNA — the first mitochondrially-encoded peptide with systemic hormonal action.
AMPK activation increases glucose uptake in skeletal muscle cells independent of insulin receptor signalling.
MOTS-c circulates systemically and translocates to the nucleus under metabolic stress — a novel peptide mechanism.
Exercise increases endogenous MOTS-c levels — research into its role as an exercise-mimetic continues.
Administration Reference
Subcutaneous administration in abdominal or outer thigh sites. Some research models have used intramuscular delivery to the vastus lateralis. Administration proximate to exercise bouts has been explored to study metabolic synergy.
Documented Combination Protocols
Mitochondrial peptide stack — MOTS-c (metabolic AMPK) + Humanin (cytoprotection and IGF axis).
Core mitochondrial research combination: NAD+ as coenzyme substrate + MOTS-c AMPK activation.
Dual AMPK activation research — MOTS-c (mitochondrial) + AICAR (nucleotide-mediated), comparing mechanisms.
IMPORTANT RESEARCH DISCLAIMER
This compound is for in-vitro research and laboratory use only. It has not been evaluated or approved by any regulatory authority for human therapeutic use. It must not be used as a food, drug, or cosmetic. SYNTHEXA assumes no liability for misuse. Handle in accordance with Good Laboratory Practice.